Zepbound (tirzepatide) produced substantial average weight loss in clinical trials, but the price without insurance is confusing. Here is what it actually costs each month in Utah when you pay yourself, including our visit fees, so you can plan ahead.
LillyDirect self-pay vial prices
Eli Lilly sells Zepbound single-dose vials directly to self-pay patients through LillyDirect. Prices below are as of October 2026; Lilly can change them, and the pharmacy confirms the price at checkout.
Zepbound vials (pharmacy)
2.5 mg (starting dose)$299/mo
5 mg$399/mo
7.5, 10, 12.5 or 15 mg$449/mo*
*Prices are per 28-day supply (4 vials). The $449 price requires each refill within 45 days of the last one; otherwise Lilly lists $499 for 7.5 mg and $699 for 10 to 15 mg.
Your visits (Restoration Health)
New weight-loss patient visit$199
Monthly follow-up visit$149
Paid when you book online. No insurance needed.
Your real monthly total
Month 1
About $498
$199 first visit + $299 for 2.5 mg
Month 2
About $548
$149 visit + $399 for 5 mg
Higher doses
About $598
$149 visit + $449 for 7.5 to 15 mg
Zepbound pens bought without insurance cost far more than the vials, so we usually prescribe vials for self-pay patients. Looking for a lower monthly cost? The Wegovy pill runs about $448 a month on its top dose, including visits.
How vials work
- Each vial is one weekly dose. You draw it up with a syringe and inject under the skin once a week; we teach you how at your visit.
- We send your prescription to LillyDirect’s self-pay pharmacy, which ships to your home in Utah.
- You start at 2.5 mg. If it is working and you tolerate it, the dose may go up in 2.5 mg steps after at least 4 weeks on each dose; the usual maintenance doses are 5, 10 or 15 mg.
What results to expect
In the SURMOUNT-1 trial, which combined the medicine with diet and activity changes, adults without diabetes lost on average about 15% to 21% of body weight over 72 weeks, depending on dose, compared with about 3% on placebo. These are averages, not a promise; individual results vary. Benefits, side effects and warnings are explained on our GLP-1 medications page.
Important safety information
- Boxed warning: thyroid C-cell tumors were seen in rodents; it is not known whether this happens in people. Do not use tirzepatide if you or a family member has had medullary thyroid cancer, or if you have MEN 2.
- Do not use during pregnancy or after a serious allergic reaction to the medicine. Tell us if you are planning a pregnancy.
- Serious risks include pancreatitis, gallbladder problems, kidney problems from dehydration, serious allergic reactions, worsening of diabetic eye disease, and low blood sugar when combined with insulin or a sulfonylurea.
- Birth control (tirzepatide): birth-control pills may work less well; use a non-oral method or add a backup method for 4 weeks after starting and after each dose increase.
- Before sedation or surgery, tell the team you take it; it slows stomach emptying.
- Most common side effects: nausea, diarrhea, vomiting, constipation and stomach pain.
Read the full Zepbound Prescribing Information and Medication Guide, and our GLP-1 medications guide.
Ways to keep costs down
- Refill on time. Missing the 45-day window raises the vial price at higher doses.
- Stay on the lowest dose that works. Not everyone needs 15 mg; we adjust based on your results and side effects.
- Track at home. Weights and readings shared between visits help us decide dose changes. See virtual monitoring.
- Ask about other options. For some patients, phentermine or the Wegovy pill is a better fit for budget or preference.
Had a sleeve or bypass and regained weight? Early studies suggest tirzepatide may help, though the evidence is still limited. Read GLP-1s for weight regain after bariatric surgery.
Ready to talk it through?
Book a visit in person in Lehi or by secure video. New weight-loss patient visit $199; monthly follow-up visit $149. Medication is billed separately by your pharmacy. See all prices.
Frequently asked questions
How much is Zepbound without insurance?
As of October 2026, LillyDirect lists single-dose vials at $299 per 28-day supply (4 vials) for 2.5 mg, $399 for 5 mg, and $449 for 7.5 mg through 15 mg when each refill ships within 45 days of the last one. Pens cost much more without insurance.
What is the 45-day refill rule?
For the 7.5 mg to 15 mg vials, the $449 price applies when each refill is filled within 45 days of the previous one. Outside that window, Lilly lists $499 for 7.5 mg and $699 for 10 mg to 15 mg. Staying on schedule matters.
What will I pay in total each month?
About $498 in the first month ($199 first visit + $299 for 2.5 mg) and about $598 a month at doses of 7.5 mg to 15 mg ($149 monthly visit + $449 medication per 28-day supply). Medication is paid to the pharmacy; visits are paid to us.
Is Zepbound the same as Mounjaro?
Both contain tirzepatide. Zepbound is the version approved for chronic weight management and for moderate to severe obstructive sleep apnea in adults with obesity; Mounjaro is approved for type 2 diabetes.
Do you prescribe compounded tirzepatide?
No. We prescribe FDA-approved Zepbound and help you use the manufacturer self-pay program.
Related guides
- GLP-1 medications: how they work, benefits and side effects
- Wegovy pill in Utah: self-pay cost and how to start
- GLP-1s for weight regain after bariatric surgery
- Phentermine: in-person start, short-term use and side effects
- Virtual monitoring: smart scales, glucose and blood pressure
- Medical Weight Loss program overview
- All self-pay prices
- Primary care for our weight-loss patients
- Browse all patient guides
Reviewed by a fellowship-trained physician at Restoration Health Medical Group. Last updated October 2026. This page is general information, not medical advice for you; whether a medication is right for you is decided at your visit. For a medical emergency, call 911.